Modern surgery requires advanced
materials for wound closing that can be fast and reversibly fixed to
tissue. Such materials will save surgery time, improve reliability of
suturing process, reduce scar tissue and traumatisation and enhance
cosmesis. Within the BMBF funded cooperative project “FixNaht” we
develope innovative solutions for the fabrication of self-retaining
sutures and meshes based on bioinspired strategies for enhancing
adhesion and grip to tissue. Polymeric fibers applied in surgery are
patterned with nanofibrils with different geometries. The nanofibrillar
topography resembles that of gecko toe pads and is expected to allow
strong fixation via directed mechanical interlocking with the tissue.
As polymer chemists we focus on the process and materials development
and we closely cooperate with pathologists (University Mainz),
physicists (INM Saarbrücken) and surgeons in order to understand
intereaction mechanisms, to assess biocompatibility issues and special
needs at their point-of-application.